Comparative in vitro activity by mouth Antimicrobial agents against Intestinal disease of patients with Community acquired urinary tract infections in three European countries
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Comparative in vitro activity by mouth Antimicrobial agents against Intestinal disease of patients with Community acquired urinary tract infections in three European countries
abstract
Enterobacteriaceae causing community-acquired urinary tract
infections were examined in selected outpatient clinics and hospitals
in Belgium, Germany and Spain using EUCAST breakpoints for
susceptibility. A total of 1190 isolates were collected. Escherichia coli
isolates were resistant to amoxicillin–clavulanic acid (28.1%),
ciprofloxacin (23.4%) and trimethoprim–sulfamethoxazole (21.4%)
compared with fosfomycin and nitrofurantoin (each, <1.5%).
Ceftibuten (MIC
50/90
0.25/0.5 mg/L) and ceftriaxone activity (MIC
0.25 mg/L) was comparable. Ceftibuten (MIC
0.25 mg/L) was
also active against Proteus mirabilis and Klebsiella spp. Extendedspectrum
β-lactamase phenotypes were 7.1% for E. coli, 5.6% for
Klebsiella pneumoniae and 0.4% for P. mirabilis. Resistance was
common among men and elderly women.
Clinical Microbiology and Infection © 2015 European Society of
Clinical Microbiology and Infectious Diseases. Published by Elsevier
Ltd. All rights reserved.
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